ATG10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-13109

Novus Biologicals, part of Bio-Techne
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NBP3-13109
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all ATG10 Antibodies »

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ATG10. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Centrifuge briefly prior to opening.

Scientific Data Images for ATG10 Antibody

Western Blot: ATG10 Antibody [NBP3-13109]

Western Blot: ATG10 Antibody [NBP3-13109]

Western Blot: ATG10 Antibody [NBP3-13109] - Various whole cell extracts (40 ug) were separated by 12% SDS-PAGE, and the membrane was blotted with ATG10 antibody (NBP3-13109) diluted at 1:500. The signal was developed with Trident ECL plus-Enhanced.
Immunohistochemistry-Paraffin: ATG10 Antibody [NBP3-13109]

Immunohistochemistry-Paraffin: ATG10 Antibody [NBP3-13109]

Immunohistochemistry-Paraffin: ATG10 Antibody [NBP3-13109] - ATG10 antibody detects ATG10 protein at cytoplasm in human ovarian cancer by immunohistochemical analysis. Sample: Paraffin-embedded human ovarian cancer. ATG10 antibody (NBP3-13109) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

Applications for ATG10 Antibody

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ATG10

Atg10 is a major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. APG10 interacts with LC3A to facilitate the conjugation of ATG12 to ATG5. APG10 is also able to directly interact either with ATG5 or ATG7A. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies.

Long Name

Autophagy Related 10 Homolog

Alternate Names

APG10, APG10L, PP12616

Gene Symbol

ATG10

Additional ATG10 Products

Product Documents for ATG10 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ATG10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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