BAI1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB100-59011

Novus Biologicals, part of Bio-Techne
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NB100-59011
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Key Product Details

Species Reactivity

Validated:

Human, Bovine, Monkey

Predicted:

Canine (94%), Hamster (94%), Mouse (94%), Primate (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

0.7 mg/ml

View all BAI1 Antibodies »

Product Specifications

Immunogen

Synthetic 18 amino acid peptide from N-terminus of human BAI1.

Epitope

N-terminal domain of human

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (89%), Opossum (83%).

Specificity

Human BAI1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for BAI1 Antibody - BSA Free

Immunohistochemistry-Paraffin: BAI1 Antibody - BSA Free [NB100-59011]

Immunohistochemistry-Paraffin: BAI1 Antibody - BSA Free [NB100-59011]

Immunohistochemistry-Paraffin: BAI1 Antibody - BSA Free [NB100-59011] - Analysis of anti-BAI1 antibody with human prostate.

Applications for BAI1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100 - 1:2000

Immunohistochemistry-Paraffin

10-15 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

0.7 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: BAI1

Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wild type p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas

Long Name

Brain-specific Angiogenesis Inhibitor 1

Alternate Names

brain-specific angiogenesis inhibitor 1, FLJ41988, GDAIF

Entrez Gene IDs

575 (Human)

Gene Symbol

ADGRB1

Additional BAI1 Products

Product Documents for BAI1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for BAI1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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