BAIAP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15545

Novus Biologicals, part of Bio-Techne
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NBP2-15545
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (98%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all BAIAP2 Antibodies »

Product Summary for BAIAP2 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human BAIAP2. The exact sequence is proprietary.

Localization

Cytoplasm; Membrane; Cell projection; filopodium; ruffle

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

61 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for BAIAP2 Antibody

Western Blot: BAIAP2 Antibody [NBP2-15545]

Western Blot: BAIAP2 Antibody [NBP2-15545]

Western Blot: BAIAP2 Antibody [NBP2-15545] - Various tissue extracts (50 ug) were separated by 10% SDS-PAGE, and the membrane was blotted with BAIAP2 antibody diluted at 1:10000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.
Immunocytochemistry/ Immunofluorescence: BAIAP2 Antibody [NBP2-15545]

Immunocytochemistry/ Immunofluorescence: BAIAP2 Antibody [NBP2-15545]

Immunocytochemistry/Immunofluorescence: BAIAP2 Antibody [NBP2-15545] - Confocal immunofluorescence analysis of methanol-fixed A431, using BAIAP2 antibody (Green) at 1:500 dilution. Alpha-tubulin filaments are labeled with Alpha-tubulin antibody (Red) at 1:2000.
Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP2-15545]

Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP2-15545]

Immunohistochemistry-Paraffin: BAIAP2 Antibody [NBP2-15545] - Paraffin-embedded mouse brain. BAIAP2 antibody diluted at 1:500.
View 1 more images

Applications for BAIAP2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:20000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: BAIAP2

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alternate Names

BAI1-associated protein 2IRS-58, BAI-associated protein 2, BAP2, brain-specific angiogenesis inhibitor 1-associated protein 2, Fas ligand-associated factor 3, FLAF3, Insulin receptor substrate p53, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa, IRSp53, IRSp53/58, Protein BAP2

Gene Symbol

BAIAP2

UniProt

Q9UQB8 (Human)

Additional BAIAP2 Products

Product Documents for BAIAP2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for BAIAP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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