BAP1 Antibody (BAP1/6861R)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-13801

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # BAP1/6861R

Concentration

0.2 mg/ml

View all BAP1 Antibodies »

Product Specifications

Immunogen

Recombinant fragment (around aa400-729) of human BAP1 protein (exact sequence is proprietary) (Uniprot: Q92560)

Localization

Nuclear, Cytoplasm

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Theoretical MW

91 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-14042)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.

Scientific Data Images for BAP1 Antibody (BAP1/6861R)

Immunohistochemistry-Paraffin: BAP1 Antibody (BAP1/6861R) [NBP3-13801]

Immunohistochemistry-Paraffin: BAP1 Antibody (BAP1/6861R) [NBP3-13801]

Immunohistochemistry-Paraffin: BAP1 Antibody (BAP1/6861R) [NBP3-13801] - Formalin-fixed, paraffin-embedded human breast carcinoma stained with BAP1 antibody (BAP1/6861R). Inset: PBS instead of primary, secondary antibody control.
Immunohistochemistry-Paraffin: BAP1 Antibody (BAP1/6861R) [NBP3-13801]

Immunohistochemistry-Paraffin: BAP1 Antibody (BAP1/6861R) [NBP3-13801]

Immunohistochemistry-Paraffin: BAP1 Antibody (BAP1/6861R) [NBP3-13801] - Formalin-fixed, paraffin-embedded human breast carcinoma stained with BAP1 antibody (BAP1/6861R).

Applications for BAP1 Antibody (BAP1/6861R)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: BAP1

BRCA1-associated protein 1 (BAP1) is a ubiquitin hydrolase that acts as a BRCA1 growth control pathway tumor suppressor. Specifically, BAP-1 localizes to the nucleus where it interferes with the BRCA1/BARD1 heterodimer activity and mediates deubiquitination of histone H2A and HCFC1. BAP 1 is highly expressed in testis, placenta, breast and ovary.

Long Name

BRCA1-associated protein 1

Alternate Names

Cerebral Protein-6, UCHL2

Gene Symbol

BAP1

UniProt

Q92560 (Human)

Additional BAP1 Products

Product Documents for BAP1 Antibody (BAP1/6861R)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for BAP1 Antibody (BAP1/6861R)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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