BCR Antibody (1E11G12) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61707

Novus Biologicals, part of Bio-Techne
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NBP2-61707
NBP2-61707-0.025ml
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Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 1E11G12

Format

BSA Free

Concentration

1 mg/ml

View all BCR Antibodies »

Product Summary for BCR Antibody (1E11G12) - BSA Free

Immunogen

Purified recombinant fragment of human BCR (AA: 139-280) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

142.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for BCR Antibody (1E11G12) - BSA Free

Western Blot: BCR Antibody (1E11G12)BSA Free [NBP2-61707]

Western Blot: BCR Antibody (1E11G12)BSA Free [NBP2-61707]

Western Blot: BCR Antibody (1E11G12) [NBP2-61707] - Analysis using BCR mAb against HEK293 (1) and BCR (AA: 139-280)-hIgGFc transfected HEK293 (2) cell lysate.
Flow Cytometry: BCR Antibody (1E11G12) - BSA Free [NBP2-61707]

Flow Cytometry: BCR Antibody (1E11G12) - BSA Free [NBP2-61707]

Flow Cytometry: BCR Antibody (1E11G12) [NBP2-61707] - Analysis of K562 cells using BCR mouse mAb (green) and negative control (red).
Western Blot: BCR Antibody (1E11G12)BSA Free [NBP2-61707]

Western Blot: BCR Antibody (1E11G12)BSA Free [NBP2-61707]

Western Blot: BCR Antibody (1E11G12) [NBP2-61707] - Analysis using BCR mAb against human BCR (AA: 139-280) recombinant protein. (Expected MW is 41.6 kDa)
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Applications for BCR Antibody (1E11G12) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Flow Cytometry

1:200-1:400

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BCR

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

Long Name

Breakpoint Cluster Region

Alternate Names

ALL, PHL

Gene Symbol

BCR

Additional BCR Products

Product Documents for BCR Antibody (1E11G12) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for BCR Antibody (1E11G12) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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