beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-19788

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.11 mg/ml

View all beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibodies »

Product Specifications

Immunogen

A synthetic peptide made to an N-terminal portion of the human B3TGAT1 protein (between residues 1-50) [UniProt Q9P2W7]

Localization

Golgi apparatus membrane; Single-pass type II membrane protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody - BSA Free [NBP1-19788]

Immunocytochemistry/ Immunofluorescence: beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody - BSA Free [NBP1-19788]

Immunocytochemistry/Immunofluorescence: beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody [NBP1-19788] - Antibody was tested in U2OS cells with FITC (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red).
Immunohistochemistry: beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody - BSA Free [NBP1-19788]

Immunohistochemistry: beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody - BSA Free [NBP1-19788]

Immunohistochemistry: beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody [NBP1-19788] - Analysis in mouse brain using DAB with hematoxylin counterstain.

Applications for beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunohistochemistry-Paraffin

1:400
Application Notes
Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS and 30% Glycerol

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1.11 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: beta-1,3-Glucuronyltransferase 1/B3GAT1

CD57 (also known as beta-1,3-glucuronyltransferase 1, Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, Glucuronosyltransferase P, Human Natural Killer 1, B3GAT1, NK1, HNK1, LEU7, NK-1, GLCUATP, and GLCATP) is a member of the glucuronyltransferase gene family. The enzymes produced by the members of this family recognize non-reducing terminal sugars and their anomeric linkages by exhibiting strong acceptor specificity. CD57 is also involved in the biosynthesis of glycosaminoglycan and L2/HNK-1 carbohydrate epitopes on glycoproteins. CD57 is expressed mainly in the brain and several alternate transcriptional splice variants have been characterized. In cancer research, CD57 positive lymphocytes have been used successfully in monitoring the progression of various cancers (PMID: 21491089). HNK1 is also involved in synaptic plasticity and neurodevelopment (PMID: 20950796).

Long Name

UDP-GlcUA:glycoprotein beta-1,3-Glucuronyltransferase

Alternate Names

CD57, GLCATP, GLCUATP, HNK1, LEU7

Entrez Gene IDs

27087 (Human)

Gene Symbol

B3GAT1

UniProt

Q9P2W7

Additional beta-1,3-Glucuronyltransferase 1/B3GAT1 Products

Product Documents for beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for beta-1,3-Glucuronyltransferase 1/B3GAT1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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