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beta-Glucuronidase/GUSB Antibody (SR2217)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22347

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-22347-100ul
NBP3-22347-50ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2217

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for beta-Glucuronidase/GUSB Antibody (SR2217)

Immunogen

A synthesized peptide derived from human beta-Glucuronidase/GUSB (Uniprot #: P08236)

Specificity

Detects endogenous levels of total beta-Glucuronidase/GUSB

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

78 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for beta-Glucuronidase/GUSB Antibody (SR2217)

Western Blot: beta-Glucuronidase/GUSB Antibody (SR2217) [NBP3-22347] -

Western Blot: beta-Glucuronidase/GUSB Antibody (SR2217) [NBP3-22347] - Western blot analysis using NBP3-22347 in K562 cell lysate.

Applications for beta-Glucuronidase/GUSB Antibody (SR2217)

Application
Recommended Usage

Flow Cytometry

1:50

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: beta-Glucuronidase/GUSB

The GUSB gene encodes beta-glucuronidase (EC 3.2.1.31), a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans (Shipley et al., 1993 [PubMed 7680524]). It is a tetrameric glycoprotein composed of identical subunits (Oshima et al., 1987 [PubMed 3468507]). The GUSB gene is mutated in mucopolysaccharidosis type VII (MPS7; MIM 253220).[supplied by OMIM]

Alternate Names

Beta-G1, MPS7

Gene Symbol

GUSB

Additional beta-Glucuronidase/GUSB Products

Product Documents for beta-Glucuronidase/GUSB Antibody (SR2217)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for beta-Glucuronidase/GUSB Antibody (SR2217)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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