beta-Glucuronidase/GUSB Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00002990-B01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all beta-Glucuronidase/GUSB Antibodies »

Product Specifications

Immunogen

GUSB (NP_000172.1, 1 a.a. - 651 a.a.) full-length human protein. MARGSAVAWAALGPLLWGCALGLQGGMLYPQESPSRECKELDGLWSFRADFSDNRRRGFEEQWYRRPLWESGPTVDMPVPSSFNDISQDWRLRHFVGWVWYEREVILPERWTQDLRTRVVLRIGSAHSYAIVWVNGVDTLEHEGGYLPFEADISNLVQVGPLPSRLRITIAINNTLTPTTLPPGTIQYLTDTSKYPKGYFVQNTYFDFFNYAGLQRSVLLYTTPTTYIDDITVTTSVEQDSGLVNYQISVKGSNLFKLEVRLLDAENKVVANGTGTQGQLKVPGVSLWWPYLMHERPAYLYSLEVQLTAQTSLGPVSDFYTLPVGIRTVAVTKSQFLINGKPFYFHGVNKHEDADIRGKGFDWPLLVKDFNLLRWLGANAFRTSHYPYAEEVMQMCDRYGIVVIDECPGVGLALPQFFNNVSLHHHMQVMEEVVRRDKNHPAVVMWSVANEPASHLESAGYYLKMVIAHTKSLDPSRPVTFVSNSNYAADKGAPYVDVICLNSYYSWYHDYGHLELIQLQLATQFENWYKKYQKPIIQSEYGAETIAGFHQDPPLMFTEEYQKSLLEQYHLGLDQKRRKYVVGELIWNFADFMTEQSPTRVLGNKKGIFTRQRQPKSAAFLLRERYWKIANETRYPHSVAKSQCLENSPFT

Specificity

Reacts with glucuronidase, beta.

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for beta-Glucuronidase/GUSB Antibody

Western Blot: beta-Glucuronidase/GUSB Antibody [H00002990-B01P]

Western Blot: beta-Glucuronidase/GUSB Antibody [H00002990-B01P]

Western Blot: beta-Glucuronidase/GUSB Antibody [H00002990-B01P] - Analysis of GUSB expression in human liver.
Western Blot: beta-Glucuronidase/GUSB Antibody [H00002990-B01P]

Western Blot: beta-Glucuronidase/GUSB Antibody [H00002990-B01P]

Western Blot: beta-Glucuronidase/GUSB Antibody [H00002990-B01P] - Analysis of GUSB expression in transfected 293T cell line by GUSB polyclonal antibody. Lane 1: GUSB transfected lysate(71.61 KDa). Lane 2: Non-transfected lysate.

Applications for beta-Glucuronidase/GUSB Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against tissue and transfected lysate in WB and as a detection antibody in ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: beta-Glucuronidase/GUSB

The GUSB gene encodes beta-glucuronidase (EC 3.2.1.31), a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans (Shipley et al., 1993 [PubMed 7680524]). It is a tetrameric glycoprotein composed of identical subunits (Oshima et al., 1987 [PubMed 3468507]). The GUSB gene is mutated in mucopolysaccharidosis type VII (MPS7; MIM 253220).[supplied by OMIM]

Alternate Names

Beta-G1, MPS7

Entrez Gene IDs

2990 (Human)

Gene Symbol

GUSB

UniProt

NP_000172.1 (Human)

Additional beta-Glucuronidase/GUSB Products

Product Documents for beta-Glucuronidase/GUSB Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for beta-Glucuronidase/GUSB Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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