beta Sarcoglycan Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59751

Novus Biologicals, part of Bio-Techne
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NBP1-59751
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all beta-Sarcoglycan Antibodies »

Product Summary for beta Sarcoglycan Antibody

Immunogen

Synthetic peptides corresponding to SGCB(sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)) The peptide sequence was selected from the middle region of SGCB. Peptide sequence FSTDYETHEFHLPSGVKSLNVQKASTERITSNATSDLNIKVDGRAIVRGN. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for beta Sarcoglycan Antibody

Western Blot: beta Sarcoglycan Antibody [NBP1-59751]

Western Blot: beta Sarcoglycan Antibody [NBP1-59751]

Western Blot: beta Sarcoglycan Antibody [NBP1-59751] - Titration: 0.2-1 ug/ml, Positive Control: Human heart.
Western Blot: beta Sarcoglycan Antibody [NBP1-59751]

Western Blot: beta Sarcoglycan Antibody [NBP1-59751]

Western Blot: beta Sarcoglycan Antibody [NBP1-59751] - Tissue: Human Fetal Heart

Applications for beta Sarcoglycan Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: beta-Sarcoglycan

SGCB is a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix.The dystrophin-glycoprotein complex (DGC) is a multisubunit protein complex that spans the sarcolemma and provides structural linkage between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. There are 3 main subcomplexes of the DGC: the cytoplasmic proteins dystrophin (DMD; MIM 300377) and syntrophin (SNTA1; MIM 601017), the alpha- and beta-dystroglycans (see MIM 128239), and the sarcoglycans (see, e.g., SGCA; MIM 600119) (Crosbie et al., 2000 [PubMed 10942431]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1235 BC020709.1 1-1235 1236-1833 U31116.1 1257-1854 1834-4229 AK094731.1 47-2442

Alternate Names

43DAG, A3b, beta Sarcoglycan, Beta-SG, Sarcoglycan beta, SGC, SGCB

Gene Symbol

SGCB

UniProt

Q16585 (Human)

Additional beta-Sarcoglycan Products

Product Documents for beta Sarcoglycan Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for beta Sarcoglycan Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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