beta Sarcoglycan Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-38648

Novus Biologicals, part of Bio-Techne
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NBP3-38648SS
NBP3-38648
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1.0 mg/ml

View all beta-Sarcoglycan Antibodies »

Product Specifications

Immunogen

Partial recombinant protein made to the C-terminal portion of human beta Sarcoglycan [UniProt Q16585].

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for beta Sarcoglycan Antibody

beta Sarcoglycan Antibody

Beta Sarcoglycan in Human Kidney Tissue.

Beta Sarcoglycan was detected in immersion fixed paraffin-embedded sections of human kidney tissue using 0.5 µg/mL Rabbit Anti-Human beta Sarcoglycan Affinity-purified Polyclonal Antibody (Catalog # NBP3-38648) overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained with the Anti-Rabbit HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
beta Sarcoglycan Antibody

Beta Sarcoglycan in Human Heart Tissue.

Beta Sarcoglycan was detected in immersion fixed paraffin-embedded sections of human heart tissue using 0.5 µg/mL Rabbit Anti-Human beta Sarcoglycan Affinity-purified Polyclonal Antibody (Catalog # NBP3-38648) overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained with the Anti-Rabbit HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Applications for beta Sarcoglycan Antibody

Application
Recommended Usage

Immunohistochemistry

1:100 - 1:500

Immunohistochemistry-Paraffin

1:100 - 1:500
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.02% Sodium Azide

Concentration

1.0 mg/ml

Stability & Storage

Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C.

Background: beta-Sarcoglycan

The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac and smooth muscle fibers. Four sarcoglycan subunit proteins, designated alpha-, beta-, gamma- and delta-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, beta- and delta-sarcoglycans are associated with episilon-sarcoglycan, a glycoprotein homologous to alpha-sarcoglycan. Additionally, a complete deficiency in delta-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.

Alternate Names

43DAG, A3b, beta Sarcoglycan, Beta-SG, Sarcoglycan beta, SGC, SGCB

Gene Symbol

SGCB

Additional beta-Sarcoglycan Products

Product Documents for beta Sarcoglycan Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for beta Sarcoglycan Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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