BIN1 Antibody (1H1)

Novus Biologicals, part of Bio-Techne | Catalog # H00000274-M01

Novus Biologicals, part of Bio-Techne
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H00000274-M01
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 1H1

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all BIN1 Antibodies »

Product Specifications

Immunogen

BIN1 (NP_004296, 355 a.a. ~ 454 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. VVETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPFQNPEEQDEGWLMGVKESDWNQHKELEKCRGVFPENFTERVP

Specificity

BIN1 - bridging integrator 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for BIN1 Antibody (1H1)

Western Blot: BIN1 Antibody (1H1) [H00000274-M01]

Western Blot: BIN1 Antibody (1H1) [H00000274-M01]

Western Blot: BIN1 Antibody (1H1) [H00000274-M01] - Analysis of BIN1 expression in transfected 293T cell line by BIN1 monoclonal antibody (M01), clone 1H1.Lane 1: BIN1 transfected lysate(53 KDa).Lane 2: Non-transfected lysate.
Western Blot: BIN1 Antibody (1H1) [H00000274-M01]

Western Blot: BIN1 Antibody (1H1) [H00000274-M01]

Western Blot: BIN1 Antibody (1H1) [H00000274-M01] - BIN1 monoclonal antibody (M01), clone 1H1 Analysis of BIN1 expression in Hela S3 NE.

Applications for BIN1 Antibody (1H1)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: BIN1

This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynanim, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

Alternate Names

AMPH2, Amphiphysin II, Amphiphysin-like protein, AMPHLDKFZp547F068, box dependant MYC interacting protein 1, bridging integrator 1Box-dependent myc-interacting protein 1, MGC10367, myc box-dependent-interacting protein 1, SH3P9

Entrez Gene IDs

274 (Human)

Gene Symbol

BIN1

OMIM

601248 (Human)

UniProt

NP_004296 (Human)

Additional BIN1 Products

Product Documents for BIN1 Antibody (1H1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for BIN1 Antibody (1H1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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