BLNK Antibody (1D7)

Novus Biologicals, part of Bio-Techne | Catalog # H00029760-M04

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Rat

Applications

ELISA, Proximity Ligation Assay, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 1D7

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all BLNK Antibodies »

Product Specifications

Immunogen

BLNK (AAH18906, 301 a.a. ~ 400 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRF

Specificity

BLNK - B-cell linker (1D7)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for BLNK Antibody (1D7)

Western Blot: BLNK Antibody (1D7) [H00029760-M04]

Western Blot: BLNK Antibody (1D7) [H00029760-M04]

Western Blot: BLNK Antibody (1D7) [H00029760-M04] - Analysis of BLNK expression in IMR-32.
Western Blot: BLNK Antibody (1D7) [H00029760-M04]

Western Blot: BLNK Antibody (1D7) [H00029760-M04]

Western Blot: BLNK Antibody (1D7) [H00029760-M04] - Analysis of BLNK expression in rat brain.
Proximity Ligation Assay: BLNK Antibody (1D7) [H00029760-M04]

Proximity Ligation Assay: BLNK Antibody (1D7) [H00029760-M04]

Proximity Ligation Assay: BLNK Antibody (1D7) [H00029760-M04] - Analysis of protein-protein interactions between NCK1 and BLNK. HeLa cells were stained with anti-NCK1 rabbit purified polyclonal 1:1200 and anti-BLNK mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction com

Applications for BLNK Antibody (1D7)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody Reactive Against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: BLNK

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

B-cell Linker Protein

Alternate Names

BASH, Ly57, SLP65

Entrez Gene IDs

29760 (Human)

Gene Symbol

BLNK

UniProt

AAH18906 (Human)

Additional BLNK Products

Product Documents for BLNK Antibody (1D7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for BLNK Antibody (1D7)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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