BLNK Antibody (SR2143)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22546

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22546-100ul
NBP3-22546-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2143

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all BLNK Antibodies »

Product Summary for BLNK Antibody (SR2143)

Immunogen

A synthesized peptide derived from human BLNK (Uniprot #: Q8WV28)

Specificity

Detects endogenous levels of total BLNK

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

70 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for BLNK Antibody (SR2143)

Western Blot: BLNK Antibody (SR2143) [NBP3-22546] -

Western Blot: BLNK Antibody (SR2143) [NBP3-22546] - Western blot analysis using NBP3-22546 in Raji cell lysate.

Applications for BLNK Antibody (SR2143)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BLNK

B-cell linker protein (BLNK, also known as SLP65, BASH, and BCA) is a B cell adaptor that plays an important role in B cell development and in BCR-signal transduction. Since BLNK does not encode any intrinsic enzymatic activity, its function is to serve as a scaffold for assembling macromolecular complexes which includes enzymes (PLC gamma, Vav and Btk) and additional linker proteins (Grb2 and Nck) (1-3). In addition, BLNK binds Btk and is required for activation of the transcription factor NF-

Long Name

B-cell Linker Protein

Alternate Names

BASH, Ly57, SLP65

Gene Symbol

BLNK

Additional BLNK Products

Product Documents for BLNK Antibody (SR2143)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for BLNK Antibody (SR2143)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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