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BLOS3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-98303

Novus Biologicals, part of Bio-Techne
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NBP1-98303

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

Product Summary for BLOS3 Antibody

Immunogen

The immunogen for this antibody is BLOS3 - N-terminal region (NP_997715). Peptide sequence RGRPTGLRVAGEAAETDSEPEPEPEPTAAPRDLPPLVVQRESAEEAWGTE. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

21 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for BLOS3 Antibody

Western Blot: BLOS3 Antibody [NBP1-98303]

Western Blot: BLOS3 Antibody [NBP1-98303]

Western Blot: BLOS3 Antibody [NBP1-98303] - Antibody Dilution: 1.0ug/ml Sample Tissue: Human heart.

Applications for BLOS3 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BLOS3

This gene encodes a protein that is a component of the BLOC1 multi-subunit protein complex. This complex is necessary for the biogenesis of specialized organelles of the endosomal-lysosomal system, including platelet dense granules and melanosomes. Mutations in this gene cause Hermansky-Pudlak syndrome 8, a disease characterized by lysosomal storage defects, bleeding due to platelet storage pool deficiency, and oculocutaneous albinism.

Alternate Names

biogenesis of lysosomal organelles complex-1, subunit 3, biogenesis of lysosome-related organelles complex 1 subunit 3, BLOS3, HPS8, RP

Entrez Gene IDs

388552 (Human)

Gene Symbol

BLOC1S3

UniProt

Additional BLOS3 Products

Product Documents for BLOS3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for BLOS3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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