BOB1 Antibody (RM378)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-77435

Recombinant Monoclonal Antibody.
Novus Biologicals, part of Bio-Techne
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NBP2-77435
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # RM378

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all BOB1 Antibodies »

Product Specifications

Immunogen

A peptide corresponding to the C-terminus of human BOB1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for BOB1 Antibody (RM378)

Western Blot: BOB1 Antibody (RM378) [NBP2-77435]

Western Blot: BOB1 Antibody (RM378) [NBP2-77435]

Western Blot: BOB1 Antibody (RM378) [NBP2-77435] - Western Blot of Daudi cells lysate using NBP2-77435.
Immunohistochemistry: BOB1 Antibody (RM378) [NBP2-77435]

Immunohistochemistry: BOB1 Antibody (RM378) [NBP2-77435]

Immunohistochemistry: BOB1 Antibody (RM378) [NBP2-77435] - Immunohistochemical staining of formalin fixed and paraffin embedded human tonsil tissue section using NBP2-77435.

Applications for BOB1 Antibody (RM378)

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2000

Western Blot

1:5000 - 1:10000

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50% Glycerol/PBS, 1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: BOB1

BOB1 is a novel 35kDa protein designated Bob1 (B cell Oct binding protein 1) is a lymphocyte specific transcription co activator protein. B cell specific transcription is mediated by octamer motifs found in immunoglobulin heavy and light chain gene promoters and in some immunoglobulin enhancers. These sites are bound by the B cell specific Oct1 and Oct2 transcription factors, and the B cell restricted co activator BOB.1/OBF.1. This protein interacts only with the Oct1/2 proteins through sub domains in the POU domain of the Oct1/2 proteins, enhancing their transcriptional efficacy. Although having no intrinsic capacity for DNA binding, Bob1 associates tightly with the octomer motif in the presence of Oct1 and Oct2. Bob1 is expressed at highest levels in spleen and peripheral blood leukocytes.

Alternate Names

B-cell-specific coactivator OBF-1, BOB-1, OBF-1, OBF1BOB1, OCAB, OCA-B, OCT-binding factor 1, POU class 2 associating factor 1, POU domain class 2, associating factor 1, POU domain class 2-associating factor 1, POU domain, class 2, associating factor 1

Gene Symbol

POU2AF1

Additional BOB1 Products

Product Documents for BOB1 Antibody (RM378)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for BOB1 Antibody (RM378)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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