BPNT1 Antibody (2E1)

Novus Biologicals, part of Bio-Techne | Catalog # H00010380-M01

Novus Biologicals, part of Bio-Techne
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H00010380-M01
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 2E1

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all BPNT1 Antibodies »

Product Specifications

Immunogen

BPNT1 (NP_006076, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MASSNTVLMRLVASAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGEEDLPSEEVDQELIEDSQWEEILKQPC

Reactivity Notes

Human. Other species not tested.

Specificity

BPNT1 - 3'(2'), 5'-bisphosphate nucleotidase 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for BPNT1 Antibody (2E1)

Western Blot: BPNT1 Antibody (2E1) [H00010380-M01]

Western Blot: BPNT1 Antibody (2E1) [H00010380-M01]

Western Blot: BPNT1 Antibody (2E1) [H00010380-M01] - BPNT1 monoclonal antibody (M01), clone 2E1 Analysis of BPNT1 expression in HeLa.
Immunocytochemistry/ Immunofluorescence: BPNT1 Antibody (2E1) [H00010380-M01]

Immunocytochemistry/ Immunofluorescence: BPNT1 Antibody (2E1) [H00010380-M01]

Immunocytochemistry/Immunofluorescence: BPNT1 Antibody (2E1) [H00010380-M01] - Analysis of monoclonal antibody to BPNT1 on HeLa cell. Antibody concentration 10 ug/ml.
Immunohistochemistry-Paraffin: BPNT1 Antibody (2E1) [H00010380-M01]

Immunohistochemistry-Paraffin: BPNT1 Antibody (2E1) [H00010380-M01]

Immunohistochemistry-Paraffin: BPNT1 Antibody (2E1) [H00010380-M01] - Analysis of monoclonal antibody to BPNT1 on formalin-fixed paraffin-embedded human pancreas. Antibody concentration 3 ug/ml.
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Applications for BPNT1 Antibody (2E1)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunofluoresence, immunohistochemistry (paraffin), and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: BPNT1

BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

Alternate Names

3'(2'), 5'-bisphosphate nucleotidase 1,3'(2')5'-bisphosphate nucleotidase 1, Bisphosphate 3'-nucleotidase 1, BPntase, EC 3.1.3, EC 3.1.3.7, PAP-inositol-1,4-phosphatase, PIP

Entrez Gene IDs

10380 (Human)

Gene Symbol

BPNT1

OMIM

604053 (Human)

UniProt

NP_006076 (Human)

Additional BPNT1 Products

Product Documents for BPNT1 Antibody (2E1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for BPNT1 Antibody (2E1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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