BPNT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-68164

Novus Biologicals, part of Bio-Techne
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NB100-68164
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all BPNT1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-RNYDYYASRVPESIK corresponding to C-Terminus according to NP_006076.4.

Epitope

RNYDYYASRVPESIK

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for BPNT1 Antibody

Western Blot: BPNT1 Antibody [NB100-68164]

Western Blot: BPNT1 Antibody [NB100-68164]

Western Blot: BPNT1 Antibody [NB100-68164] - Analysis of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for BPNT1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:4000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 37 kDa band observed in human liver lysates is reported in scientific literature (PMID: 10224133).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: BPNT1

BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

Alternate Names

3'(2'), 5'-bisphosphate nucleotidase 1,3'(2')5'-bisphosphate nucleotidase 1, Bisphosphate 3'-nucleotidase 1, BPntase, EC 3.1.3, EC 3.1.3.7, PAP-inositol-1,4-phosphatase, PIP

Entrez Gene IDs

10380 (Human); 23827 (Mouse); 64473 (Rat)

Gene Symbol

BPNT1

UniProt

NP_006076.4 (Human)

Additional BPNT1 Products

Product Documents for BPNT1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for BPNT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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