BPNT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14359

Novus Biologicals, part of Bio-Techne
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NBP2-14359
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all BPNT1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: SEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVTVLIGIAYEGKAIAGVINQPYYNYEAGP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for BPNT1 Antibody

Western Blot: BPNT1 Antibody [NBP2-14359]

Western Blot: BPNT1 Antibody [NBP2-14359]

Western Blot: BPNT1 Antibody [NBP2-14359] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4
Immunocytochemistry/ Immunofluorescence: BPNT1 Antibody [NBP2-14359]

Immunocytochemistry/ Immunofluorescence: BPNT1 Antibody [NBP2-14359]

Immunocytochemistry/Immunofluorescence: BPNT1 Antibody [NBP2-14359] - Immunofluorescent staining of human cell line HEK 293 shows localization to nuclear speckles.
Immunohistochemistry-Paraffin: BPNT1 Antibody [NBP2-14359]

Immunohistochemistry-Paraffin: BPNT1 Antibody [NBP2-14359]

Immunohistochemistry-Paraffin: BPNT1 Antibody [NBP2-14359] - Staining of human kidney shows strong cytoplasmic positivity in renal tubules.

Applications for BPNT1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BPNT1

BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

Alternate Names

3'(2'), 5'-bisphosphate nucleotidase 1,3'(2')5'-bisphosphate nucleotidase 1, Bisphosphate 3'-nucleotidase 1, BPntase, EC 3.1.3, EC 3.1.3.7, PAP-inositol-1,4-phosphatase, PIP

Gene Symbol

BPNT1

Additional BPNT1 Products

Product Documents for BPNT1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for BPNT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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