BPTF/FALZ Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57567

Novus Biologicals, part of Bio-Techne
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NBP2-57567
NBP2-57567-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (90%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all BPTF/FALZ Antibodies »

Product Summary for BPTF/FALZ Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: TTIASTGQTFQITGNPVTMAGKVITKLPLPANSKIVAVNVPATQGGIVQVHQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for BPTF/FALZ Antibody

Immunocytochemistry/ Immunofluorescence: BPTF/FALZ Antibody [NBP2-57567]

Immunocytochemistry/ Immunofluorescence: BPTF/FALZ Antibody [NBP2-57567]

Immunocytochemistry/Immunofluorescence: BPTF/FALZ Antibody [NBP2-57567] - Staining of human cell line U-251 MG shows localization to nucleoplasm.

Applications for BPTF/FALZ Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BPTF/FALZ

FALZ/BPTF is a histone-binding component of NURF (nucleosome remodeling factor), a complex that catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. This gene was identified in brain homogenates from patients with Alzheimer's disease. Analysis of the original protein (fetal Alz-50 reactive clone 1, or FAC1), containing a DNA-binding domain, a zinc finger motif, and a C-terminal bromodomain, suggested it might play a role in the regulation of transcription during proliferation. High levels of FAC1 were detected in fetal brain and in patients with neurodegenerative diseases. This protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex.

Long Name

Nucleosome-remodeling factor subunit BPTF

Alternate Names

BPTF, FAC1, FALZ

Gene Symbol

BPTF

Additional BPTF/FALZ Products

Product Documents for BPTF/FALZ Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for BPTF/FALZ Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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