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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # OCA125/2349R

Format

Azide and BSA Free

Concentration

1 mg/ml

Product Specifications

Immunogen

Purified human CA125/MUC16 protein (Uniprot: Q8WXI7)

Localization

Cell Surface and Secreted

Marker

Ovarian Carcinoma Marker

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

1.0 mg/ml of antibody purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS WITHOUT BSA & azide. Also available at 200 ug/ml WITH BSA & azide (NBP3-07573).

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for CA125/MUC16 Antibody (OCA125/2349R) - Azide and BSA Free

Immunohistochemistry-Paraffin: CA125/MUC16 Antibody (OCA125/2349R) - Azide and BSA Free [NBP3-08371]

Immunohistochemistry-Paraffin: CA125/MUC16 Antibody (OCA125/2349R) - Azide and BSA Free [NBP3-08371]

Immunohistochemistry-Paraffin: CA125/MUC16 Antibody (OCA125/2349R) - Azide and BSA Free [NBP3-08371] - Formalin-fixed, paraffin-embedded human Ovarian Carcinoma stained with CA125/MUC16 Rabbit Recombinant Monoclonal Antibody (OCA125/2349R).
Immunohistochemistry-Paraffin: CA125/MUC16 Antibody (OCA125/2349R) - Azide and BSA Free [NBP3-08371]

Immunohistochemistry-Paraffin: CA125/MUC16 Antibody (OCA125/2349R) - Azide and BSA Free [NBP3-08371]

Immunohistochemistry-Paraffin: CA125/MUC16 Antibody (OCA125/2349R) - Azide and BSA Free [NBP3-08371] - Formalin-fixed, paraffin-embedded human Endometrial Carcinoma stained with CA125/MUC16 Rabbit Recombinant Monoclonal Antibody (OCA125/2349R).

Applications for CA125/MUC16 Antibody (OCA125/2349R) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry Formalin-fixed: 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20 to -80C. Avoid freeze-thaw cycles.

Background: CA125/MUC16

MUC16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is over expressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller "subunits" being described by some investigators.

Long Name

Ovarian Cancer Antigen CA125

Alternate Names

MUC16

Gene Symbol

MUC16

Additional CA125/MUC16 Products

Product Documents for CA125/MUC16 Antibody (OCA125/2349R) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CA125/MUC16 Antibody (OCA125/2349R) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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