CACNA1E Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11901

Novus Biologicals, part of Bio-Techne
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NBP3-11901-100ug
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CACNA1E Antibodies »

Product Specifications

Immunogen

Synthetic peptide derived from the rat alpha1E calcium channel conjugated to KLH (Uniprot: Q07652)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for CACNA1E Antibody

Application
Recommended Usage

Western Blot

5 - 10 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Ammonium sulfate precipitation

Formulation

PBS

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CACNA1E

Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel, and partially by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), omega-conotoxin-GVIA (omega-CTx-GVIA), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels contaning alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.; Subcellular location: Membrane; Multi-pass membrane protein.; Tissue specificity: Expressed in neuronal tissues and in kidney.

Long Name

Voltage-dependent R-type calcium channel subunit alpha-1E

Alternate Names

BII, CACH6, CACNL1A6

Gene Symbol

CACNA1E

UniProt

Q07652 (Rat)

Additional CACNA1E Products

Product Documents for CACNA1E Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CACNA1E Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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