CACNA1E Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-43404

Novus Biologicals, part of Bio-Techne
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NBP3-43404
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Key Product Details

Species Reactivity

Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Serum, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all CACNA1E Antibodies »

Product Specifications

Immunogen

Immunized with recombinant Mouse CACNA1E (Uniprot#: Q61290; Gly246~Trp327)

Clonality

Polyclonal

Host

Rabbit

Applications for CACNA1E Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20 ug/mL

Immunohistochemistry

5-20 ug/mL

Western Blot

0.2-2 ug/mL

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH7.4, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CACNA1E

Function: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel, and partially by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to dihydropyridines (DHP), omega-conotoxin-GVIA (omega-CTx-GVIA), and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels contaning alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing.; Subcellular location: Membrane; Multi-pass membrane protein.; Tissue specificity: Expressed in neuronal tissues and in kidney.

Long Name

Voltage-dependent R-type calcium channel subunit alpha-1E

Alternate Names

BII, CACH6, CACNL1A6

Gene Symbol

CACNA1E

Additional CACNA1E Products

Product Documents for CACNA1E Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for CACNA1E Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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