CACNB3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56436

Novus Biologicals, part of Bio-Techne
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NBP2-56436
NBP2-56436-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CACNB3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: SIRLKQEQKARRSGNPSSLSDIGNRRS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CACNB3 Antibody

Immunocytochemistry/ Immunofluorescence: CACNB3 Antibody [NBP2-56436]

Immunocytochemistry/ Immunofluorescence: CACNB3 Antibody [NBP2-56436]

Immunocytochemistry/Immunofluorescence: CACNB3 Antibody [NBP2-56436] - Staining of human cell line MCF7 shows localization to vesicles.

Applications for CACNB3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CACNB3

The CACNB3 gene encodes for a proteins that are long voltage dependent L-type calcium channel subunit beta-3 gene that aids in regulating surface expression, calcium transport, regulation of transcription factors, and gating of calcium channels. Isoform 3A is 484 amino acids in length with a mass of around 54 kDA while isoform 3B is 447 amino acids long at around 50 kDA. Increasingly, research has investigated the role of the CACNB3 gene in various diseases such as neuronitis, neuropathy, canavan disease, and lambert-eaton myasthenic syndrome. This gene plays a role in many pathways such as CREB transcription, the Celecoxib pathway, MAPK signaling pathway, and the Myometrial Relaxation and Contraction pathways and is known to interact with various other genes such as: CACNA1C, CACNA1B, SYT1, FASLG, and YWHAB.

Alternate Names

CAB3, CACNLB3, Calcium channel voltage-dependent subunit beta 3, calcium channel, voltage-dependent, beta 3 subunit, voltage-dependent L-type calcium channel subunit beta-3

Gene Symbol

CACNB3

Additional CACNB3 Products

Product Documents for CACNB3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CACNB3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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