CACNB4 Antibody (7E1)

Novus Biologicals, part of Bio-Techne | Catalog # H00000785-M01-100ug

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 7E1

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CACNB4 Antibodies »

Product Specifications

Immunogen

CACNB4 (NP_000717.2, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDED

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for CACNB4 Antibody (7E1)

Western Blot: CACNB4 Antibody (7E1) [H00000785-M01-100ug]

Western Blot: CACNB4 Antibody (7E1) [H00000785-M01-100ug]

Western Blot: CACNB4 Antibody (7E1) [H00000785-M01-100ug] - Detection against Immunogen (37.84 KDa) .
Western Blot: CACNB4 Antibody (7E1) [H00000785-M01-100ug]

Western Blot: CACNB4 Antibody (7E1) [H00000785-M01-100ug]

Western Blot: CACNB4 Antibody (7E1) [H00000785-M01-100ug] - Analysis of CACNB4 expression in K-562.
ELISA: CACNB4 Antibody (7E1) [H00000785-M01-100ug]

ELISA: CACNB4 Antibody (7E1) [H00000785-M01-100ug]

ELISA: CACNB4 Antibody (7E1) [H00000785-M01-100ug] - Detection limit for recombinant GST tagged CACNB4 is 0.03 ng/ml as a capture antibody.

Applications for CACNB4 Antibody (7E1)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CACNB4

CACNB4 encodes a member of the beta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein described in this record plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME). Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.

Long Name

Voltage-dependent L-type calcium channel subunit beta-4

Alternate Names

CAB4, CACNLB4

Entrez Gene IDs

785 (Human)

Gene Symbol

CACNB4

OMIM

600669 (Human)

UniProt

NP_000717.2 (Human)

Additional CACNB4 Products

Product Documents for CACNB4 Antibody (7E1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CACNB4 Antibody (7E1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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