Cactin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-70775

Novus Biologicals, part of Bio-Techne
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NBP1-70775
NBP1-70775SS
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Key Product Details

Species Reactivity

Validated:

Human, Porcine, Bovine, Canine, Primate

Predicted:

Chimpanzee (100%), Opossum (100%), Rhesus Macaque (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Cactin Antibodies »

Product Specifications

Immunogen

A portion of amino acid 460-510 of human Cactin was used as the immunogen.

Reactivity Notes

Predicted to react with Bacteria, Mosquito, Mouse, Pufferfish, Rat, Wild Turkey, Zebrafish.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cactin Antibody

Western Blot: Cactin Antibody [NBP1-70775]

Western Blot: Cactin Antibody [NBP1-70775]

Western Blot: Cactin Antibody [NBP1-70775] - analysis of Cactin. Lanes 1 and 2 show human heart tissue lysate probed with pre-immune sera (1:5000) and Cactin polyclonal antibody (7 ug/ml), respectively.
Immunohistochemistry-Paraffin: Cactin Antibody [NBP1-70775]

Immunohistochemistry-Paraffin: Cactin Antibody [NBP1-70775]

Immunohistochemistry-Paraffin: Cactin Antibody [NBP1-70775] - staining of human brain using Cactin polyclonal antibody at 5 ug/ml.

Applications for Cactin Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

5-7 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS containing 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cactin

Cactin is a novel negative regulator of TLR signaling and reveals its capacity to target MHC Class III genes at the molecular and functional level. It is localized to the nucleus, which is critical for manifesting its inhibitory effects on TLR signaling. Experimental evidences show overexpression of Cactin suppresses TLR-induced activation of NF-kB and interferon-regulatory factor transcription factors and induction of TLR-responsive genes. It is also reported Cactin interacts with IkB-like protein and targets other proteins that are encoded by genes in the MHC Class III region of chromosome 6.

Alternate Names

C19orf29, cactin, cactin homolog, cactin, spliceosome C complex subunit, chromosome 19 open reading frame 29, FLJ17482, FLJ59622, fSAPc, functional spliceosome-associated protein c, NY REN 24 antigen, NY-REN-24, NY-REN-24 antigen

Gene Symbol

CACTIN

UniProt

Q8WUQ7 (Human)

Additional Cactin Products

Product Documents for Cactin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cactin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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