Cadherin-16 Antibody (rCDH16/7342)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20395

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG1 kappa Clone # rCDH16/7342

Concentration

0.2 mg/ml

View all Cadherin-16 Antibodies »

Product Specifications

Immunogen

Recombinant human full-length Cadherin-16 protein

Localization

Cell surface. Cytoplasm.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Positive Controls: Normal kidney or renal cell carcinoma.

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C. Non-hazardous. No MSDS required.

Scientific Data Images for Cadherin-16 Antibody (rCDH16/7342)

Cadherin-16 Antibody (rCDH16/7342)

Cadherin-16 Antibody (rCDH16/7342)

IHC analysis of formalin-fixed, paraffin-embedded normal human kidney. Stained using Cadherin-16 antibody (rCDH16/7342) at 2ug/ml in PBS for 30min RT. Inset: PBS instead of primary antibody; secondary only negative control.
Cadherin-16 Antibody (rCDH16/7342)

Immunohistochemistry-Paraffin: Cadherin-16 Antibody (rCDH16/7342) [NBP3-20395] -

Immunohistochemistry-Paraffin: Cadherin-16 Antibody (rCDH16/7342) [NBP3-20395] - IHC analysis of formalin-fixed, paraffin-embedded normal human kidney. Stained using Cadherin-16 antibody (rCDH16/7342) at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. Secondary: HRP-polymer, 30min. DAB, 5min.

Applications for Cadherin-16 Antibody (rCDH16/7342)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes. at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.

Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

10mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Cadherin-16

Cadherin 16 is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development.

Alternate Names

cadherin 16, KSP-cadherin, cadherin-16, Kidney-specific cadherin, Ksp-cadherin

Gene Symbol

CDH16

Additional Cadherin-16 Products

Product Documents for Cadherin-16 Antibody (rCDH16/7342)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cadherin-16 Antibody (rCDH16/7342)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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