Cadherin-16 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34028

Novus Biologicals, part of Bio-Techne
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NBP2-34028
NBP2-34028-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cadherin-16 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: NSHVVYQLLSPEPEDGVEGRAFQVDPTSGSVTLGVLPLRAGQNILLLVLAMDLAGAEGGFSSTCEVEVAVTDINDHAPEFITSQIGPISLPEDVEPGTLVAMLTAIDADLEPAFRLMDFAIERGDTEGTFGLDWEPDS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cadherin-16 Antibody

Western Blot: Cadherin-16 Antibody [NBP2-34028]

Western Blot: Cadherin-16 Antibody [NBP2-34028]

Western Blot: Cadherin-16 Antibody [NBP2-34028] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10
Lane 2: Human Kidney tissue
Immunohistochemistry-Paraffin: Cadherin-16 Antibody [NBP2-34028]

Immunohistochemistry-Paraffin: Cadherin-16 Antibody [NBP2-34028]

Immunohistochemistry-Paraffin: Cadherin-16 Antibody [NBP2-34028] - Staining in human kidney and lymph node tissues using anti-CDH16 antibody. Corresponding CDH16 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Cadherin-16 Antibody [NBP2-34028]

Immunohistochemistry-Paraffin: Cadherin-16 Antibody [NBP2-34028]

Immunohistochemistry-Paraffin: Cadherin-16 Antibody [NBP2-34028] - Staining of human kidney shows high expression.
View 1 more images

Applications for Cadherin-16 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cadherin-16

Cadherin 16 is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development.

Alternate Names

cadherin 16, KSP-cadherin, cadherin-16, Kidney-specific cadherin, Ksp-cadherin

Gene Symbol

CDH16

UniProt

O75309 (Human)

Additional Cadherin-16 Products

Product Documents for Cadherin-16 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cadherin-16 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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