Cadherin-17 Antibody (CDH17/2618)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-79723

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP2-79723-100ug
NBP2-79723-20ug
Print Quote
Bulk Order
Forumulation
Catalog #
BSA Free
NBP2-79857
View Product
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # CDH17/2618

Concentration

0.2 mg/ml

View all Cadherin-17 Antibodies »

Product Specifications

Immunogen

Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17) (exact sequence is proprietary) (Uniprot: Q12864)

Localization

Cell Surface, Cytoplasm

Marker

Liver-Intestine Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Theoretical MW

120 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

200ug/ml of antibody purified from rabbit anti-serum by Protein A. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0 mg/ml. (NBP2-79857)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for Cadherin-17 Antibody (CDH17/2618)

Immunohistochemistry-Paraffin: Cadherin-17 Antibody (CDH17/2618) [NBP2-79723]

Immunohistochemistry-Paraffin: Cadherin-17 Antibody (CDH17/2618) [NBP2-79723]

Immunohistochemistry-Paraffin: Cadherin-17 Antibody (CDH17/2618) [NBP2-79723] - Formalin-fixed, paraffin-embedded human Colon stained with Cadherin-17 Antibody (CDH17/2618).
Flow Cytometry: Cadherin-17 Antibody (CDH17/2618) [NBP2-79723]

Flow Cytometry: Cadherin-17 Antibody (CDH17/2618) [NBP2-79723]

Flow Cytometry: Cadherin-17 Antibody (CDH17/2618) [NBP2-79723] - Flow Cytometric Analysis of MCF-7 cells using Cadherin-17 Antibody (CDH17/2618)followed by Goat anti-Mouse IgG-CF488 (Blue); Isotype Control (Red).
Protein Array: Cadherin-17 Antibody (CDH17/2618) [NBP2-79723]

Protein Array: Cadherin-17 Antibody (CDH17/2618) [NBP2-79723]

Protein Array: Cadherin-17 Antibody (CDH17/2618) [NBP2-79723] - Analysis of Protein Array containing more than 19,000 full-length human proteins using Cadherin-17 Antibody (CDH17/2618). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5.

Applications for Cadherin-17 Antibody (CDH17/2618)

Application
Recommended Usage

Flow Cytometry

1-2 ug/million cells

Immunohistochemistry

1-2 ug/ml

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Cadherin-17

LI Cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine.

Alternate Names

Cadherin17, CDH17

Gene Symbol

CDH17

UniProt

Q12864 (Human)

Additional Cadherin-17 Products

Product Documents for Cadherin-17 Antibody (CDH17/2618)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Cadherin-17 Antibody (CDH17/2618)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.