Calneuron 1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76274

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Calneuron 1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CaBP8. The immunogen is located within the first 50 amino acids of CaBP8. Amino Acid Squence: CEEPPRSQAPDFPTWEK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Calneuron 1 Antibody - BSA Free

Western Blot: Calneuron 1 AntibodyBSA Free [NBP1-76274]

Western Blot: Calneuron 1 AntibodyBSA Free [NBP1-76274]

Western Blot: Calneuron 1 Antibody [NBP1-76274] - 3T3 cell lysate with CaBP8 antibody at (A) 1 and (B) 2 ug/mL.

Applications for Calneuron 1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Calneuron 1

Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP8, contains two EF-hand domains for calcium binding and shares 70% homology with CaBP7 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. Both CaBP8 and CaBP7 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.

Alternate Names

CaBP8, calcium-binding protein 8, calcium-binding protein CABP8, calneuron 1, Calneuron I, calneuron-1

Gene Symbol

CALN1

UniProt

NP_113656 (Human)

Additional Calneuron 1 Products

Product Documents for Calneuron 1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Calneuron 1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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