Calponin 2 Antibody (4C9)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-42944

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Porcine

Applications

ELISA, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # 4C9

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Calponin 2 Antibodies »

Product Specifications

Immunogen

calponin 2 - (Uniprot# Q99439)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Theoretical MW

36 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Applications for Calponin 2 Antibody (4C9)

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:4000

Western Blot

1:1000 - 1:4000

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS (pH 7.3), 50% glycerol

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Calponin 2

Calponin, a 34 kDa protein, regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an actin- and tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Calponin is implicated in the regulation of smooth muscle contraction through its interaction with F-actin and inhibition of the actin-activated MgATPase activity of phosphorylated myosin.Both properties are lost following phosphorylation (primarily at serine 175) by protein kinase C or calmodulin-dependent protein kinase II. The three forms of Calponin, Calponin 1 (basic Calponin), Calponin 2 (neutral Calponin), and Calponin 3 (acidic Calponin) are found in smooth muscle tissue. Additionally, Calponin 2 is found in heart muscle tissue and Calponin 3 is found in the brain.

Alternate Names

calponin 2, Calponin H2, smooth muscle, calponin-2, Neutral calponin

Gene Symbol

CNN2

Additional Calponin 2 Products

Product Documents for Calponin 2 Antibody (4C9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Calponin 2 Antibody (4C9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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