Calsenilin Antibody (2B3-A1)

Novus Biologicals, part of Bio-Techne | Catalog # H00030818-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 2B3-A1

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Calsenilin Antibodies »

Product Specifications

Immunogen

CSEN (AAH12850, 1 a.a. ~ 256 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MQPAKEVTKASDGSLLGDLGHTPLSKKEGIKWQRPRLSRQALMRCCLVKWILSSTAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYAQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI

Reactivity Notes

Human. Other species not tested.

Specificity

CSEN - calsenilin, presenilin binding protein, EF-hand transcription factor

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for Calsenilin Antibody (2B3-A1)

Western Blot: Calsenilin Antibody (2B3-A1) [H00030818-M01]

Western Blot: Calsenilin Antibody (2B3-A1) [H00030818-M01]

Western Blot: Calsenilin Antibody (2B3-A1) [H00030818-M01] - Analysis of KCNIP3 expression in transfected 293T cell line by CSEN monoclonal antibody (M01), clone 2B3-A1.Lane 1: KCNIP3 transfected lysate (Predicted MW: 29.2 KDa).Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: Calsenilin Antibody (2B3-A1) [H00030818-M01]

Immunocytochemistry/ Immunofluorescence: Calsenilin Antibody (2B3-A1) [H00030818-M01]

Immunocytochemistry/Immunofluorescence: Calsenilin Antibody (2B3-A1) [H00030818-M01] - Analysis of monoclonal antibody to CSEN on HeLa cell . Antibody concentration 10 ug/ml.
Immunoprecipitation: Calsenilin Antibody (2B3-A1) [H00030818-M01]

Immunoprecipitation: Calsenilin Antibody (2B3-A1) [H00030818-M01]

Immunoprecipitation: Calsenilin Antibody (2B3-A1) [H00030818-M01] - Analysis of KCNIP3 transfected lysate using anti-KCNIP3 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with KCNIP3 MaxPab rabbit polyclonal antibody.
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Applications for Calsenilin Antibody (2B3-A1)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control. It is also useful for immunofluorescence.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Calsenilin

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternate Names

calsenilin, calsenilin, presenilin-binding protein, EF hand transcription factor, CSEN MGC18289, DREAM, DREAMA-type potassium channel modulatory protein 3, KChIP3, KCHIP3 DRE-antagonist modulator, Kv channel interacting protein 3, calsenilin, Kv channel-interacting protein 3, potassium channel interacting protein 3

Entrez Gene IDs

30818 (Human)

Gene Symbol

KCNIP3

OMIM

604662 (Human)

UniProt

AAH12850 (Human)

Additional Calsenilin Products

Product Documents for Calsenilin Antibody (2B3-A1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Calsenilin Antibody (2B3-A1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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