Calsequestrin 2 Antibody (1B6)

Novus Biologicals, part of Bio-Techne | Catalog # H00000845-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 1B6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Calsequestrin 2 Antibodies »

Product Specifications

Immunogen

CASQ2 (AAH22288, 20 a.a. ~ 399 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. EEGLNFPTYDGKDRVVSLSEKNFKQVLKKYDLLCLYYHEPVSSDKVTQKQFQLKEIVLELVAQVLEHKAIGFVMVDAKKEAKLAKKLGFDEEGSLYILKGDRTIEFDGEFAADVLVEFLLDLIEDPVEIISSKLEVQAFERIEDYIKLIGFFKSEDSEYYKAFEEAAEHFQPYIKFFATFDKGVAKKLSLKMNEVDFYEPFMDEPIAIPNKPYTEEELVEFVKEHQRPTLRRLRPEEMFETWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTDNPDLSILWIDPDDFPLLVAYWEKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTEDDDEDDDDDDNSDEEDNDDSDDDDDE

Specificity

CASQ2 - calsequestrin 2 (cardiac muscle)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Calsequestrin 2 Antibody (1B6)

Western Blot: Calsequestrin 2 Antibody (1B6) [H00000845-M01]

Western Blot: Calsequestrin 2 Antibody (1B6) [H00000845-M01]

Western Blot: Calsequestrin 2 Antibody (1B6) [H00000845-M01] - Analysis of CASQ2 expression in transfected 293T cell line by CASQ2 monoclonal antibody (M01), clone 1B6.Lane 1: CASQ2 transfected lysate(46.4 KDa).Lane 2: Non-transfected lysate.
Sandwich ELISA: Calsequestrin 2 Antibody (1B6) [H00000845-M01] - Detection limit for recombinant GST tagged CASQ2 is approximately 0.3ng/ml as a capture antibody.

Applications for Calsequestrin 2 Antibody (1B6)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Calsequestrin 2

The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.

Alternate Names

calsequestrin 2 (cardiac muscle), calsequestrin 2, fast-twitch, cardiac muscle, Calsequestrin, cardiac muscle isoform, calsequestrin-2, FLJ26321, FLJ93514, PDIB2

Entrez Gene IDs

845 (Human)

Gene Symbol

CASQ2

UniProt

AAH22288 (Human)

Additional Calsequestrin 2 Products

Product Documents for Calsequestrin 2 Antibody (1B6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Calsequestrin 2 Antibody (1B6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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