CAMP/Cathelicidin Antibody (SR2385)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27689

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-27689
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2385

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CAMP/Cathelicidin Antibodies »

Product Summary for CAMP/Cathelicidin Antibody (SR2385)

Immunogen

A synthetic peptide of human CAMP/Cathelicidin (Uniprot #: P49913)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

19 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CAMP/Cathelicidin Antibody (SR2385)

CAMP/Cathelicidin Antibody (SR2385)

Western Blot: CAMP/Cathelicidin Antibody (SR2385) [NBP3-27689] -

Western Blot: CAMP/Cathelicidin Antibody (SR2385) [NBP3-27689] - Western blot analysis in Human serum lysates

Applications for CAMP/Cathelicidin Antibody (SR2385)

Application
Recommended Usage

Immunohistochemistry

1:50-1:100

Immunoprecipitation

1:20

Western Blot

1:500-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CAMP/Cathelicidin

Cathelicidins are a family of antimicrobial proteins predominantly found in the peroxidase negative granules of neutrophils. The cathelicidins are synthesized as preproproteins. Within the neutrophils, they are stored in granules as inactive proforms after removal of the signal peptide. The active biologic domains of the cathelicidins generally reside in the C terminus. The C terminal antimicrobial peptides are activated when cleaved from the proforms of the cathelicidins by serine proteases from azurophil granules. FUNCTION: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. SUBCELLULAR LOCATION: Secreted. TISSUE SPECIFICITY: Expressed in bone marrow and testis and neutrophils.

Alternate Names

18 kDa cationic antimicrobial protein, Antibacterial peptide FALL-39, CAP18, CAP-18, cathelicidin antimicrobial peptide, CRAMP, epididymis secretory sperm binding protein, FALL39, FALL-39, FALL-39 peptide antibiotic, hCAP-181, HSD26, LL37

Gene Symbol

CAMP

Additional CAMP/Cathelicidin Products

Product Documents for CAMP/Cathelicidin Antibody (SR2385)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CAMP/Cathelicidin Antibody (SR2385)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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