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CAMP/Cathelicidin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88203

Novus Biologicals, part of Bio-Techne
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NBP1-88203
NBP1-88203-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCMGTVTLNQARGSFDISCDKDNKRFALLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CAMP/Cathelicidin Antibody

Immunohistochemistry-Paraffin: CAMP/Cathelicidin Antibody [NBP1-88203]

Immunohistochemistry-Paraffin: CAMP/Cathelicidin Antibody [NBP1-88203]

Immunohistochemistry-Paraffin: CAMP/Cathelicidin Antibody [NBP1-88203] - CAMP/LL37/FALL39/Cathelicidin Antibody [NBP1-88203] - Staining in human bone marrow and cerebral cortex tissues . Corresponding CAMP RNA-seq data are presented for the same tissues.
Western Blot: CAMP/Cathelicidin Antibody [NBP1-88203]

Western Blot: CAMP/Cathelicidin Antibody [NBP1-88203]

Western Blot: CAMP/LL37/FALL39/Cathelicidin Antibody [NBP1-88203] - Analysis in human plasma.
Immunohistochemistry-Paraffin: CAMP/Cathelicidin Antibody [NBP1-88203]

Immunohistochemistry-Paraffin: CAMP/Cathelicidin Antibody [NBP1-88203]

Immunohistochemistry-Paraffin: CAMP/LL37/FALL39/Cathelicidin Antibody [NBP1-88203] - Staining of human bone marrow shows moderate to strong granular cytoplasmic positivity in hematopoietic cells.

Applications for CAMP/Cathelicidin Antibody

Application
Recommended Usage

Immunohistochemistry

1:2500 - 1:5000

Immunohistochemistry-Paraffin

1:2500 - 1:5000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CAMP/Cathelicidin

Cathelicidins are a family of antimicrobial proteins predominantly found in the peroxidase negative granules of neutrophils. The cathelicidins are synthesized as preproproteins. Within the neutrophils, they are stored in granules as inactive proforms after removal of the signal peptide. The active biologic domains of the cathelicidins generally reside in the C terminus. The C terminal antimicrobial peptides are activated when cleaved from the proforms of the cathelicidins by serine proteases from azurophil granules. FUNCTION: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. SUBCELLULAR LOCATION: Secreted. TISSUE SPECIFICITY: Expressed in bone marrow and testis and neutrophils.

Alternate Names

18 kDa cationic antimicrobial protein, Antibacterial peptide FALL-39, CAP18, CAP-18, cathelicidin antimicrobial peptide, CRAMP, epididymis secretory sperm binding protein, FALL39, FALL-39, FALL-39 peptide antibiotic, hCAP-181, HSD26, LL37

Gene Symbol

CAMP

Additional CAMP/Cathelicidin Products

Product Documents for CAMP/Cathelicidin Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CAMP/Cathelicidin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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