Carbohydrate Sulfotransferase 7/CHST7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-91248

Novus Biologicals, part of Bio-Techne
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NBP1-91248
NBP1-91248-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Carbohydrate Sulfotransferase 7/CHST7 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: PMWHLWQALYPGDAESLQGALRDMLRSLFRCDFSVLRLYAPPGDPAARAPDTANLTTAALFRWRTNKVICSPPLCPGAPRARAEVGLVEDTACERSCPPVAIRALEAECRKYPVVVIKDVRLLDLGVLVPLLRDPGLNLKVVQL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Carbohydrate Sulfotransferase 7/CHST7 Antibody

Immunohistochemistry: Carbohydrate Sulfotransferase 7/CHST7 Antibody [NBP1-91248]

Immunohistochemistry: Carbohydrate Sulfotransferase 7/CHST7 Antibody [NBP1-91248]

Immunohistochemistry: Carbohydrate Sulfotransferase 7/CHST7 Antibody [NBP1-91248] - Staining of human duodenum shows moderate cytoplasmic and membranous positivity in glandular cells.

Applications for Carbohydrate Sulfotransferase 7/CHST7 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Carbohydrate Sulfotransferase 7/CHST7

The CHST family is comprised of 14 genes in both human and mouse. All members of this family are Golgi-localized type II membrane proteins. Only the luminal and enzymatic domain is expressed in each of our recombinant CHST proteins. These enzymes transfer sulfate (i.e., sulfonate) onto the 6-O or 4-O positions of GalNAc, Gal and GlcNAc residues on glycoproteins, proteoglycans and glycolipids. This sulfation often creates specific epitopes that can be recognized by extracellular matrix proteins, cell surface receptors and viruses. CHST7, also designated as chondroitin 6-O-sulfotransferase (C6ST-2), N-acetylglucosamine-6-O-sulfotransferase (GlcNAc6ST-4) and Gal/GalNAc/GlcNAc 6-O-sulfotransferase (GST-5), was previously shown to act on chondroitin sulfate, mannose-linked GlcNAc and mucin associated GlcNAc residues. The amino acid sequence of mouse CHST7 is 87% identical to that of the human counterpart.

Alternate Names

C6ST2, CHST7, GlcNAc6ST-4, GST-5

Gene Symbol

CHST7

Additional Carbohydrate Sulfotransferase 7/CHST7 Products

Product Documents for Carbohydrate Sulfotransferase 7/CHST7 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Carbohydrate Sulfotransferase 7/CHST7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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