Carboxylesterase 1/CES1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-48854

Novus Biologicals, part of Bio-Techne
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NBP2-48854
NBP2-48854-25ul
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Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Carboxylesterase 1/CES1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: HWPEYNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQTEHIEL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Carboxylesterase 1/CES1 Antibody

Immunohistochemistry-Paraffin: Carboxylesterase 1/CES1 Antibody [NBP2-48854]

Immunohistochemistry-Paraffin: Carboxylesterase 1/CES1 Antibody [NBP2-48854]

Immunohistochemistry-Paraffin: Carboxylesterase 1/CES1 Antibody [NBP2-48854] - Analysis in human liver and cerebral cortex tissues using NBP2-48854 antibody. Corresponding CES1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Carboxylesterase 1/CES1 Antibody [NBP2-48854]

Immunohistochemistry-Paraffin: Carboxylesterase 1/CES1 Antibody [NBP2-48854]

Immunohistochemistry-Paraffin: Carboxylesterase 1/CES1 Antibody [NBP2-48854] - Staining of human cerebral cortex, liver, prostate and upper gastrointestinal using Anti-CES1 antibody NBP2-48854 (A) shows similar protein distribution across tissues to independent antibody NBP1-85691 (B).
Immunocytochemistry/ Immunofluorescence: Carboxylesterase 1/CES1 Antibody [NBP2-48854]

Immunocytochemistry/ Immunofluorescence: Carboxylesterase 1/CES1 Antibody [NBP2-48854]

Immunocytochemistry/Immunofluorescence: Carboxylesterase 1/CES1 Antibody [NBP2-48854] - Analysis of human cell line Hep G2 shows positivity in endoplasmic reticulum. Antibody staining is shown in green.
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Applications for Carboxylesterase 1/CES1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Carboxylesterase 1/CES1

Carboxylesterase 1 hydrolyzes ester- and amide bonds of substrates ranging from small molecule esters such as phenylester to long-chain fatty acid esters and thioesters. It plays a major role in the pharmacokinetic behavior of many therapeutic agents containing an ester. Through de-esterification, it participates in the detoxification of drugs such as cocaine and heroin in serum and liver.

Alternate Names

ACAT, CES1, Egasyn, HMSE1, REH, SES1, TGH

Gene Symbol

CES1

Additional Carboxylesterase 1/CES1 Products

Product Documents for Carboxylesterase 1/CES1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Carboxylesterase 1/CES1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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