CARD10 Antibody [DyLight 405]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-81970V

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CARD10/CARMA3 Antibodies »

Product Specifications

Immunogen

CARD10 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CARD10. The immunogen is located within the first 50 amino acids of CARD10. Amino Acid Squence: MPGRAEAGEAEEEAGA

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse: (81%)

Specificity

CARD10 antibody is human specific. At least three isoforms of CARD10 are known to exist; this antibody will only detect isoform 1. CARD10 antibody is predicted not to cross-react with other CARMA proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for CARD10 Antibody [DyLight 405]

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CARD10/CARMA3

The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. CARDs induce nuclear factor kappa-B (NFKB; MIM 164011) activity through the IKK (e.g., IKBKB; MIM 603258) complex. CARD9 (MIM 607212), CARD10, CARD11 (MIM 607210), and CARD14 (MIM 607211) interact with BCL10 (MIM 603517) and are involved in NFKB signaling complexes. Except for CARD9, these CARD proteins are members of the membrane-associated guanylate kinase (MAGUK) family.

Long Name

Caspase Recruitment Domain-containing Protein 10

Alternate Names

BIMP1, CARMA3

Gene Symbol

CARD10

Additional CARD10/CARMA3 Products

Product Documents for CARD10 Antibody [DyLight 405]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CARD10 Antibody [DyLight 405]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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