CASC4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-30492

Novus Biologicals, part of Bio-Techne
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NBP2-30492
NBP2-30492-25ul
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CASC4 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: NTYLVKRLEYESFQCGQQMKELRAQHEENIKKLADQFLEEQKQETQKIQSNDGKELDINNQVVPKNIPKVAENVADKNE

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (82%), Rat (82%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CASC4 Antibody

Immunocytochemistry/ Immunofluorescence: CASC4 Antibody [NBP2-30492]

Immunocytochemistry/ Immunofluorescence: CASC4 Antibody [NBP2-30492]

Immunocytochemistry/Immunofluorescence: CASC4 Antibody [NBP2-30492] - Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.
Immunohistochemistry-Paraffin: CASC4 Antibody [NBP2-30492]

Immunohistochemistry-Paraffin: CASC4 Antibody [NBP2-30492]

Immunohistochemistry-Paraffin: CASC4 Antibody [NBP2-30492] - Staining of human liver.
Immunohistochemistry: CASC4 Antibody [NBP2-30492]

Immunohistochemistry: CASC4 Antibody [NBP2-30492]

Immunohistochemistry: CASC4 Antibody [NBP2-30492] - Staining of human cerebral cortex shows strong cytoplasmic positivity with a granular pattern in neuronal cells.
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Applications for CASC4 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CASC4

The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Further characterization of the product of this gene may yield insight into the fundamental biology and pathogenetic effects of HER-2/neu overexpression in human breast and ovarian cancer cells. Alternatively spliced variants encoding different isoforms have been identified for this gene. [provided by RefSeq]

Alternate Names

cancer susceptibility candidate 4, Cancer susceptibility candidate gene 4 protein, DKFZp459F1927, gene associated with HER-2/neu overexpression, H63, MGC74708, protein CASC4

Gene Symbol

CASC4

UniProt

Q6P4E1 (Human)

Additional CASC4 Products

Product Documents for CASC4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CASC4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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