Caspase-6 Antibody (S04-5F9)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19931

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19931-100ul
NBP3-19931-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S04-5F9

Concentration

0.3 mg/ml

View all Caspase-6 Antibodies »

Product Summary for Caspase-6 Antibody (S04-5F9)

Immunogen

Recombinant protein of human Caspase-6 (Uniprot # P55212)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Caspase-6 Antibody (S04-5F9)

Western Blot: Caspase-6 Antibody (S04-5F9) [NBP3-19931]

Western Blot: Caspase-6 Antibody (S04-5F9) [NBP3-19931]

Western Blot: Caspase-6 Antibody (S04-5F9) [NBP3-19931] - Western blot detection of Caspase-6 in Jurkat, C6 cell lysates using Caspase-6 Rabbit mAb (1:1000 diluted). Predicted band size: 33kDa. Observed band size: 11kDa (cleavage), 33kDa.

Applications for Caspase-6 Antibody (S04-5F9)

Application
Recommended Usage

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Caspase-6

Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the initiation and execution of apoptosis. Caspase-6 is a major apoptotic executioner (1,2). It exists as a pro-domain protein and is cleaved by caspase-3 into two active subunits, an 18 kDa and a 10 kDa subunit (3). Caspase-6 cleaves among many different intracellular proteins, nuclear lamins. Lamins play a significant role in maintaining the integrity of the cell membrane, and their cleavage results in subsequent cellular breakdown and death (4).

Alternate Names

CASP6, Caspase6, Mch2

Gene Symbol

CASP6

Additional Caspase-6 Products

Product Documents for Caspase-6 Antibody (S04-5F9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Caspase-6 Antibody (S04-5F9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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