Caspr1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59251

Novus Biologicals, part of Bio-Techne
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NBP1-59251
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Key Product Details

Species Reactivity

Validated:

Human, Goat

Cited:

Goat

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all Caspr1 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to CNTNAP1(contactin associated protein 1) The peptide sequence was selected from the N terminal of CNTNAP1. Peptide sequence LQIDLMKKHRIRAVATQGSFNSWDWVTRYMLLYGDRVDSWTPFYQRGHNS. The peptide sequence for this immunogen was taken from within the described region.

Reactivity Notes

Goat reactivity reported in scientific literature (PMID: 31607843).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Caspr1 Antibody

Western Blot: Caspr1 Antibody [NBP1-59251]

Western Blot: Caspr1 Antibody [NBP1-59251]

Western Blot: Caspr1 Antibody [NBP1-59251] - Titration: 0.2-1 ug/ml, Positive Control: Human Lung.

Applications for Caspr1 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Application Notes
Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID:31607843).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Caspr1

CNTNAP1 was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,381-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

Long Name

Contactin Associated Protein-like 1

Alternate Names

CNTNAP, CNTNAP1, p190

Gene Symbol

CNTNAP1

UniProt

P78357 (Human)

Additional Caspr1 Products

Product Documents for Caspr1 Antibody

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Certificate of Analysis

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Product Specific Notices for Caspr1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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