Cathepsin E Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33868

Novus Biologicals, part of Bio-Techne
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NBP2-33868
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Simple Western, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cathepsin E Antibodies »

Product Summary for Cathepsin E Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: VEGLTVVGQQFGESVTEPGQTFVDAEFDGILGLGYPSLAVGGVTPVFDNMMAQNLVDLPMFSVYMSSNPEGGAGSELIFGGYDHSHFSGSLNWVPVTKQAYWQIALDN

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%), Rat (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cathepsin E Antibody

Western Blot: Cathepsin E Antibody [NBP2-33868]

Western Blot: Cathepsin E Antibody [NBP2-33868]

Western Blot: Cathepsin E Antibody [NBP2-33868] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp
Immunohistochemistry-Paraffin: Cathepsin E Antibody [NBP2-33868]

Immunohistochemistry-Paraffin: Cathepsin E Antibody [NBP2-33868]

Immunohistochemistry-Paraffin: Cathepsin E Antibody [NBP2-33868] - Staining in human stomach and liver tissues using anti-CTSE antibody. Corresponding CTSE RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Cathepsin E Antibody [NBP2-33868]

Immunohistochemistry-Paraffin: Cathepsin E Antibody [NBP2-33868]

Immunohistochemistry-Paraffin: Cathepsin E Antibody [NBP2-33868] - Staining of human liver shows low expression as expected.
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Applications for Cathepsin E Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cathepsin E

Cathepsin E (CATE) is a gastric aspartyl protease member of the peptidase C1 family that functions as a disulfide-linked homodimer. Cathepsin E may have a role in immune function. It is most likely involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. Cathepsin E may also play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.

Cathepsin E is commonly linked to gastric cancer, and Cathepsin E antibodies have emerged as important reagents for gastric cancer studies.

Alternate Names

CTSE

Gene Symbol

CTSE

UniProt

P14091 (Human)

Additional Cathepsin E Products

Product Documents for Cathepsin E Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cathepsin E Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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