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Cav1.4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-68869

Novus Biologicals, part of Bio-Techne
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NBP2-68869
NBP2-68869-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: SCEDLPIPGTYHRGRNSGPNRAQGSWATPPQRGRLLYAPLLLVEEGAAGEGYLGRSSGPLRTFTCLHVPGTHSDPSH

Reactivity Notes

Mouse 82%, Rat 83%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cav1.4 Antibody

Cav1.4 Antibody Cav1.4 Antibody

Cav1.4 Antibody [NBP2-68869] -Staining of human eye,retina shows moderate strong cytoplasmic-membranous positivity.

Cav1.4 Antibody [NBP2-68869] -Staining of human eye,retina shows moderate strong cytoplasmic-membranous positivity.
Cav1.4 Antibody Cav1.4 Antibody

Cav1.4 Antibody [NBP2-68869] -Staining of human kidney shows strong membranous positivity in cells in tubules.

Cav1.4 Antibody [NBP2-68869] -Staining of human kidney shows strong membranous positivity in cells in tubules.
Cav1.4 Antibody Cav1.4 Antibody

Cav1.4 Antibody [NBP2-68869] -Staining of human liver shows negative positivity in hepatocytes as expected.

Cav1.4 Antibody [NBP2-68869] -Staining of human liver shows negative positivity in hepatocytes as expected.

Applications for Cav1.4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
Recommended conditions for IHC,Retrieval method: HIER pH6

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cav1.4

CACNA1F encodes a member of the alpha-1 subunit family; a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants of the gene described here have been observed but have not been thoroughly characterized. Mutations in this gene have been shown to cause incomplete X-linked congential stationary night blindness type 2 (CSNB2).

Long Name

Voltage-dependent L-type calcium channel subunit alpha-1F

Alternate Names

CACNA1F, CACNAF1, CORDX3, CSNBX2

Gene Symbol

CACNA1F

Additional Cav1.4 Products

Product Documents for Cav1.4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Cav1.4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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