CBL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15730

Novus Biologicals, part of Bio-Techne
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NBP2-15730
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Rhesus Macaque (95%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CBL Antibodies »

Product Summary for CBL Antibody

Immunogen

Recombinant protein encompassing a sequence within the C-terminus region of human CBL. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

100 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CBL Antibody

Western Blot: CBL Antibody [NBP2-15730]

Western Blot: CBL Antibody [NBP2-15730]

Western Blot: CBL Antibody [NBP2-15730] - A. 30 ug THP-1 whole cell lysate/extract 7.5 % SDS-PAGE CBL antibody [C2C3], C-term dilution: 1:1000
Immunocytochemistry/ Immunofluorescence: CBL Antibody [NBP2-15730]

Immunocytochemistry/ Immunofluorescence: CBL Antibody [NBP2-15730]

Immunocytochemistry/Immunofluorescence: CBL Antibody [NBP2-15730] - Immunofluorescence analysis of methanol-fixed A431, using antibody at 1:50 dilution.

Applications for CBL Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 40% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: CBL

The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. [provided by RefSeq]

Long Name

Casitas B-lineage Lymphoma, E3 Ubiquitin Protein Ligase CBL

Alternate Names

CBL2, RNF55

Gene Symbol

CBL

UniProt

P22681 (Human)

Additional CBL Products

Product Documents for CBL Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CBL Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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