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Cbx8 Antibody (OTI3D1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46073

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI3D1

Concentration

1 mg/ml

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 1-260 of human CBX8 (NP_065700) produced in E.coli.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

43.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Cbx8 Antibody (OTI3D1)

Western Blot: Cbx8 Antibody (OTI3D1) [NBP2-46073]

Western Blot: Cbx8 Antibody (OTI3D1) [NBP2-46073]

Western Blot: Cbx8 Antibody (3D1) [NBP2-46073] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CBX8.
Immunohistochemistry: Cbx8 Antibody (OTI3D1) [NBP2-46073]

Immunohistochemistry: Cbx8 Antibody (OTI3D1) [NBP2-46073]

Immunohistochemistry: Cbx8 Antibody (3D1) [NBP2-46073] - Analysis of Carcinoma of Human thyroid tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunohistochemistry: Cbx8 Antibody (OTI3D1) [NBP2-46073]

Immunohistochemistry: Cbx8 Antibody (OTI3D1) [NBP2-46073]

Immunohistochemistry: Cbx8 Antibody (3D1) [NBP2-46073] - Analysis of Carcinoma of Human pancreas tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)

Applications for Cbx8 Antibody (OTI3D1)

Application
Recommended Usage

Immunohistochemistry

1:500

Western Blot

1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Cbx8

CBX8 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility.

Alternate Names

chromobox homolog 8, chromobox homolog 8 (Drosophila Pc class), chromobox homolog 8 (Pc class homolog, Drosophila), HPC3, Pc3, PC3chromobox protein homolog 8, polycomb 3, Polycomb 3 homolog, RC1Pc class 3 homolog, Rectachrome 1

Gene Symbol

CBX8

Additional Cbx8 Products

Product Documents for Cbx8 Antibody (OTI3D1)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Cbx8 Antibody (OTI3D1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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