CCR11 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-79925

Novus Biologicals, part of Bio-Techne
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NBP1-79925
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all CCR11 Antibodies »

Product Specifications

Immunogen

The specific Immunogen is proprietary information. Peptide sequence SIALFHSCLNPILYVFMGASFKNYVMKVAKKYGSWRRQRQSVEEFPFDSE. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

39 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for CCR11 Antibody

Western Blot: CCR11 Antibody [NBP1-79925]

Western Blot: CCR11 Antibody [NBP1-79925]

Western Blot: CCR11 Antibody [NBP1-79925] - 293T cell Lysate, concentration 1ug/ml.
Immunohistochemistry-Paraffin: CCR11 Antibody [NBP1-79925]

Immunohistochemistry-Paraffin: CCR11 Antibody [NBP1-79925]

Immunohistochemistry-Paraffin: CCR11 Antibody [NBP1-79925] - Sample Type: human colon tissues infected ex-vivo with HIV-1, Green: Primary, Blue: DAPI, Primary Dilution: 1:1000, Secondary Antibody: Donkey anti-Rabbit AF 488, Secondary Dilution: 1:500, Image Submitted By: Chiara Foglieni, San Raffaele Scientific Inst

Applications for CCR11 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CCR11

CCR11 is a G protein-coupled, seven-transmembrane receptor protein that plays a role in the chemotaxis and trafficking of leukocytes. Showing similar binding affinities as does CCR2 and CCR10 (1,2), CCR11 has been shown to specifically bind the MCP- (monocyte chemoattractant protein) family of chemokines, including MCP-4, MCP-2, and MCP-1. It was also shown to bind eotaxin (3). Though CCR11 shares functional similarity to CCR2 because it recognizes members of the MCP family, CCR11 has a distinct expression pattern (3).

Alternate Names

ACKR4, CC-CKR-11, CCRL1, CCX-CKR, PPR1, VSHK1

Gene Symbol

ACKR4

UniProt

NP_057641

Additional CCR11 Products

Product Documents for CCR11 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CCR11 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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