CCR3 Antibody (5E8-G9-B4) [CoraFluor™ 1]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-81046CL1

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP2-81046CL1
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow Cytometry

Label

CoraFluor 1

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # 5E8-G9-B4

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CCR3 Antibodies »

Product Summary for CCR3 Antibody (5E8-G9-B4) [CoraFluor™ 1]

Immunogen

CCR3

Specificity

Recognises human CCR3, a chemokine receptor highly expressed of eosinophils, as well as Th2-Tcells, basophils, platelets, mast-cells, mononuclear phagocytes, airway epithelial cells, and hematopoietic progenitor cells (CD34+).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Description

CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.

Applications for CCR3 Antibody (5E8-G9-B4) [CoraFluor™ 1]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark. Do not freeze.

Background: CCR3

CKR3, or C-C chemokine receptor type 3, is a G protein-coupled, seven-transmembrane domain receptor protein. The chemokine eotaxin appears to be a highly specific agonist for CKR3, making CKR3 one of the factors responsible for selective recruitment of eosinophils to sites of inflammation (1). It has been shown that more than one chemokine activates CKR3, including eotaxin, RANTES, and MCP-3 (2). Since CKR3 is prominently expressed in eosinophils , it has been named the human eosinophil eotaxin receptor (2,3).

Alternate Names

CCR3, CD193

Gene Symbol

CCR3

Additional CCR3 Products

Product Documents for CCR3 Antibody (5E8-G9-B4) [CoraFluor™ 1]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CCR3 Antibody (5E8-G9-B4) [CoraFluor™ 1]

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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