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CD-M6PR Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-75286

Novus Biologicals, part of Bio-Techne
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NB100-75286
NB100-75286-0.025mg

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Chicken

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for CD-M6PR Antibody

Immunogen

The immunogen for this antibody was a sequence from 60a.a. to 114a.a. from Mannose 6 Phosphate Receptor (Cation dependent)(a 277a.a. long protein)

Reactivity Notes

This antibody is reactive against Human, mouse, rat.

Localization

Membrane; single-pass type I membrane protein.

Specificity

Mannose 6 Phosphate Receptor (Cation dependent)

Marker

Late Endosome Marker

Clonality

Polyclonal

Host

Chicken

Applications for CD-M6PR Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:200 - 1:500

Western Blot

1:200 - 1:500
Application Notes
ICC: Immunocytochemistry staining of endogenous M6PR in normal rat kidney (NRK) cells. Affinity-Purified anti-M6PR IgY dilution: 1:200; Donkey anti-IgY Fc- FITC: 1:200.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2)

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD-M6PR

Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.

Long Name

Cation Dependent Mannose-6-Phosphate Receptor 46 kDa

Alternate Names

CD-MPR, CDM6PR, M6PR, MPR46, MPRD, SMPR

Entrez Gene IDs

4074 (Human); 17113 (Mouse); 312689 (Rat)

Gene Symbol

M6PR

UniProt

Additional CD-M6PR Products

Product Documents for CD-M6PR Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD-M6PR Antibody

Chicken products cannot be exported to Canada.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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