CD30/TNFRSF8 Antibody (Ber-H2 + CD30/412)

Unconjugated

Monoclonal Mouse IgG1 Kappa/IgG1 Kappa Clone # Ber-H2 + CD30/412

This product is unpurified. The exact concentration of antibody is not quantifiable.

Co cell line established from a patient with Hodgkin's disease of T-cell lineage (Ber-H2); human CD30 recombinant protein (CD30/412)

Cell surface

Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkins disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This monoclonal antibody distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).

Hodgkin & Reed-Sternberg Cell Marker

Monoclonal

Mouse

IgG1 Kappa/IgG1 Kappa

Tissue culture supernatant with 0.05% Azide.

Store at 2 to 8C.

Tissue culture supernatant

Tissue culture supernatant

0.05% Sodium Azide

This product is unpurified. The exact concentration of antibody is not quantifiable.

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C.