CD5 Antibody (OTI7A7) [Janelia Fluor® 549]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-70360JF549

Novus Biologicals, part of Bio-Techne
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NBP2-70360JF549
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Conjugate
Catalog #
Unconjugated
NBP2-02690
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Alexa Fluor 350
NBP2-70360AF350
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Alexa Fluor 405
NBP2-70360AF405
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Alexa Fluor 488
NBP2-70360AF488
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Alexa Fluor 532
NBP2-70360AF532
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Alexa Fluor 594
NBP2-70360AF594
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Alexa Fluor 647
NBP2-70360AF647
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Alexa Fluor 700
NBP2-70360AF700
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Alexa Fluor 750
NBP2-70360AF750
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Allophycocyanin
NBP2-70360APC
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Allophycocyanin/Cy7
NBP2-70360APCCY7
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Biotin
NBP2-70360B
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CoraFluor 1
NBP2-70360CL1
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DyLight 350
NBP2-70360UV
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DyLight 405
NBP2-70360V
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DyLight 488
NBP2-70360G
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DyLight 550
NBP2-70360R
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DyLight 594
NBP2-70360DL594
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DyLight 650
NBP2-70360C
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DyLight 680
NBP2-70360FR
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DyLight 755
NBP2-70360IR
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FITC
NBP2-70360F
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HRP
NBP2-70360H
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Janelia Fluor 525
NBP2-70360JF525
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Janelia Fluor 585
NBP2-70360JF585
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Janelia Fluor 635
NBP2-70360JF635
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Janelia Fluor 646
NBP2-70360JF646
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Janelia Fluor 669
NBP2-70360JF669
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mFluor Violet 450 SE
NBP2-70360MFV450
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mFluor Violet 500 SE
NBP2-70360MFV500
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mFluor Violet 610 SE
NBP2-70360MFV610
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PE
NBP2-70360PE
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PE/Atto594
NBP2-70360PEATT594
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PE/Cy5.5
NBP2-70360PECY55
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PE/Cy7
NBP2-70360PECY7
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PerCP
NBP2-70360PCP
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Janelia Fluor 549

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI7A7

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CD5 Antibodies »

Product Specifications

Immunogen

Full length recombinant protein of human CD5 (NP_055022) produced in HEK293T cells.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for CD5 Antibody (OTI7A7) [Janelia Fluor® 549]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CD5

In humans, CD5 is a 55kDa T lymphocyte single chain transmembrane glycoprotein. It is present on all mature T lymphocytes, on most thymocytes and on many T cell leukemias and lymphomas. It reacts with a subpopulation of activated B cells. CD5/Lyt1 antigen is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B cell antigen CD72. The frequency of CD5+ B cells exhibits strain dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B1 cells. Binding of CD5 on the T cell surface can augment alloantigen or mitogen induced lymphocyte proliferation and induces increased cytosolic free calcium, IL2 secretion, and IL2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T cell and B cell receptors.

Alternate Names

CD5

Gene Symbol

CD5

Additional CD5 Products

Product Documents for CD5 Antibody (OTI7A7) [Janelia Fluor® 549]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CD5 Antibody (OTI7A7) [Janelia Fluor® 549]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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