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CD8 beta Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-58425

Novus Biologicals, part of Bio-Techne
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NBP2-58425
NBP2-58425-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for CD8 beta Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: EGISGTFVPQCLHGYYSNTTTSQKLLNPWILK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CD8 beta Antibody

Immunocytochemistry/ Immunofluorescence: CD8 beta Antibody [NBP2-58425]

Immunocytochemistry/ Immunofluorescence: CD8 beta Antibody [NBP2-58425]

Immunocytochemistry/Immunofluorescence: CD8 beta Antibody [NBP2-58425] - Staining of human cell line CACO-2 shows localization to plasma membrane. Antibody staining is shown in green.

Applications for CD8 beta Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD8 beta

CD8b antigen is also known as T8, Lyt2, Ly-2, and CD8 beta. It is a member of the immunoglobulin superfamily expressed on most thymocytes, some mature T cell subsets, and macrophages. CD8b forms heterodimers with the CD8 alpha chain (CD8a). CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck).

Alternate Names

CD8 beta, CD8b, CD8B1, Leu2, LY3, LYT3, P37

Gene Symbol

CD8B

Additional CD8 beta Products

Product Documents for CD8 beta Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD8 beta Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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